Smith WT, Glaudin V, Panagides J, Gilvary E Mirtazapine vs. amitriptyline vs. placebo in the treatment of major depressive disorder. Psychopharmacol Bull 26 (1990): 191-6 Montgomery SA Safety of mirtazapine: a review. Int Clin Psychopharmacol 10(suppl 4 (1995): 37-45 View all 4 references Mirtazapine is verkrijgbaar als tablet, smelttablet of drankje. De arts stelt de aanbevolen dosis vast. Het is belangrijk dat je je hieraan houdt en dat je de tabletten consequent inneemt. Verhoog nooit zelf de dosis. Meestal is de begindosis 15 tot 30 mg per dag. Soms verhoogt de arts de dosis tot 45 mg per dag. Bij mensen met leverfunctiestoornissen of ouderen kan de dosis afwijken. De arts. Mirtazapine was administered orally to pregnant rats and rabbits during the period of organogenesis at doses of 2.5, 15, and 100 mg/kg/day and 2.5, 10, and 40 mg/kg/day, respectively, which are up to 20 and 17 times the maximum recommended human dose (MRHD) of 45 mg based on mg/m 2 body surface area, respectively. No evidence of teratogenic effects was observed. However, in rats, there was an. Mirtazapine is a newer antidepressant that exhibits both noradrenergic and serotonergic activity. It is at least as effective as the older antidepressants for treating mild to severe depression. APO-Mirtazapine 45 mg tablets. White to off-white, oval shaped, unscored, film coated tablets, imprinted APO on one side and MI-45 on the other side. 4 Clinical Particulars. 4.1 Therapeutic Indications. Treatment of major depression including relapse prevention. 4.2 Dose and Method of Administration. APO-Mirtazapine tablets are intended for oral administration. Mirtazapine should be taken. L'amitriptyline (ou amitryptyline) (commercialisé sous les noms Elavil, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Redomex) est un antidépresseur tricyclique.Il est blanc, inodore (mais a un goût de réglisse).C'est un composé cristallin très peu soluble dans l'eau ; il est généralement vendu sous forme de tablettes.